Title : Differential expression of N-myc and c-src proto-oncogenes during neuronal and schwannian differentiation of human neuroblastoma cells.

Pub. Date : 1989 Feb 15

PMID : 2917804






1 Functional Relationships(s)
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1 Decreased N-myc expression and increased c-src expression were observed during neuronal differentiation by retinoic acid, polyprenoic acid (E5166) and dibutyryl cyclic AMP, whereas the expression of N-myc and c-src genes was considerably reduced during schwannian differentiation by bromodeoxyuridine, demonstrating that the expression of N-myc and c-src genes was regulated independently in the bipolar differentiation processes of NB cells. 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid MYCN proto-oncogene, bHLH transcription factor Homo sapiens