Title : Molecular Imaging of ABCB1 and ABCG2 Inhibition at the Human Blood-Brain Barrier Using Elacridar and 11C-Erlotinib PET.

Pub. Date : 2018 Jun

PMID : 29175983






1 Functional Relationships(s)
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1 Conclusion: When Abcb1 and Abcg2 were disrupted in mice, brain uptake of 11C-erlotinib increased both at a tracer dose and at a pharmacologic dose. Erlotinib Hydrochloride ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus