Title : Interaction Effects of AFB1 and MC-LR Co-exposure with Polymorphism of Metabolic Genes on Liver Damage: focusing on SLCO1B1 and GSTP1.

Pub. Date : 2017 Nov 23

PMID : 29170472






2 Functional Relationships(s)
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1 We found that SLCO1B1 (T521C) is a risk factor for liver damage among people exposed to high AFB1 levels alone or combined with MC-LR, and that GSTP1 (A1578G) could indicate the risk of liver damage among those exposed to high MC-LR levels alone or combined with high AFB1 levels. cyanoginosin LR solute carrier organic anion transporter family member 1B1 Homo sapiens
2 In conclusion, SLCO1B1 (T521C) and GSTP1 (A1578G) are susceptible genes for liver damage in humans exposed to AFB1 and/or MC-LR in rural areas of China. cyanoginosin LR solute carrier organic anion transporter family member 1B1 Homo sapiens