Title : [Establishment of myocardial targeted nanoparticles and preliminary evaluation of its effects on prevention and treatment of myocardial injury].

Pub. Date : 2017 Nov 20

PMID : 29166707






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Results: (1) The mRNA expression of NF-kappaB-p65 of cells in Cy3-si435 group was 0.183+-0.004, significantly lower than 1.003+-0.092 in Cy3-siNC group (t=15.46, P<0.01). cy3 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 (5) The mRNA expression of NF-kappaB-p65 of cells in Cy3-si435-PAC group was 0.286+-0.015, significantly lower than 1.002+-0.073 in Cy3-siNC-PAC group (t=16.62, P<0.01). cy3 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
3 Cy3-si435-PAC nanoparticles can be effectively uptaked by HL-1 cells and suppress NF-kappaB-p65 mRNA expression. cy3 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus