Title : JQ1 synergizes with the Bcl-2 inhibitor ABT-263 against MYCN-amplified small cell lung cancer.

Pub. Date : 2017 Oct 17

PMID : 29156797






2 Functional Relationships(s)
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1 ABT-263 and JQ1 co-treatment in MYCN-amplified SCLC cells markedly disrupted Bim/Bcl-2 interaction, and prevented Bim"s interaction with Mcl-1. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid BCL2 like 11 Homo sapiens
2 ABT-263 and JQ1 co-treatment in MYCN-amplified SCLC cells markedly disrupted Bim/Bcl-2 interaction, and prevented Bim"s interaction with Mcl-1. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid BCL2 like 11 Homo sapiens