Title : Enhancing conventional chemotherapy drug cisplatin-induced anti-tumor effects on human gastric cancer cells both in vitro and in vivo by Thymoquinone targeting PTEN gene.

Pub. Date : 2017 Oct 17

PMID : 29156767






1 Functional Relationships(s)
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1 In conclusion, TQ significantly augments cisplatin-induced anti-tumor effects on gastric cancer both in vitro and in vivo, through inhibiting PI3K/AKT signaling pathway, activating the mitochondrial pathway, and down-regulating P-glycoprotein by up-regulating PTEN gene. Cisplatin ATP binding cassette subfamily B member 1 Homo sapiens