Title : The coffee diterpene kahweol enhances sensitivity to sorafenib in human renal carcinoma Caki cells through down-regulation of Mcl-1 and c-FLIP expression.

Pub. Date : 2017 Oct 10

PMID : 29137334






3 Functional Relationships(s)
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1 The coffee diterpene kahweol enhances sensitivity to sorafenib in human renal carcinoma Caki cells through down-regulation of Mcl-1 and c-FLIP expression. Sorafenib CASP8 and FADD like apoptosis regulator Homo sapiens
2 Combined treatment with sorafenib and kahweol induced down-regulation of Mcl-1 and c-FLIP expression. Sorafenib CASP8 and FADD like apoptosis regulator Homo sapiens
3 Interestingly, combined treatment with sorafenib and kahweol induced apoptotic cell death in c-FLIP overexpressed cells. Sorafenib CASP8 and FADD like apoptosis regulator Homo sapiens