Title : IL-17A improves the efficacy of mesenchymal stem cells in ischemic-reperfusion renal injury by increasing Treg percentages by the COX-2/PGE2 pathway.

Pub. Date : 2018 Apr

PMID : 29132705






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The blockage of COX-2 by celecoxib reversed the benefit of IL-pretreated 17A-MSCs on the serum PGE2 concentration, spleen and kidney Tregs percentages, serum creatinine and BUN levels, renal acute tubular necrosis scores, and serum IL-6, TNF-alpha, IFN-gamma, and IL-10 levels of IRI-pretreated mice with AKI, compared with MSCs. Celecoxib tumor necrosis factor Mus musculus