Pub. Date : 2017 Jun
PMID : 29130021
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oxygenated cholesterol derivative oxysterols are known to be endogenous ligands of the liver X receptor (LXR), a nuclear receptor with anti-cholestasis activity, whereas the sulfated oxysterols antagonize LXR signaling. | Oxysterols | nuclear receptor subfamily 1, group H, member 3 | Mus musculus |
| 2 | Oxygenated cholesterol derivative oxysterols are known to be endogenous ligands of the liver X receptor (LXR), a nuclear receptor with anti-cholestasis activity, whereas the sulfated oxysterols antagonize LXR signaling. | Oxysterols | nuclear receptor subfamily 1, group H, member 3 | Mus musculus |
| 3 | Oxygenated cholesterol derivative oxysterols are known to be endogenous ligands of the liver X receptor (LXR), a nuclear receptor with anti-cholestasis activity, whereas the sulfated oxysterols antagonize LXR signaling. | Oxysterols | nuclear receptor subfamily 1, group H, member 3 | Mus musculus |
| 4 | Oxygenated cholesterol derivative oxysterols are known to be endogenous ligands of the liver X receptor (LXR), a nuclear receptor with anti-cholestasis activity, whereas the sulfated oxysterols antagonize LXR signaling. | Oxysterols | nuclear receptor subfamily 1, group H, member 3 | Mus musculus |
| 5 | The protective effect of the STS transgene was associated with the activation of LXR and induction of LXR target genes, likely because of the increased conversion of the antagonistic oxysterol sulfates to the agonistic oxysterols. | Oxysterols | nuclear receptor subfamily 1, group H, member 3 | Mus musculus |