Title : Genistein Ameliorates Fat Accumulation Through AMPK Activation in Fatty Acid-Induced BRL Cells.

Pub. Date : 2017 Nov

PMID : 29125642






6 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Genistein Ameliorates Fat Accumulation Through AMPK Activation in Fatty Acid-Induced BRL Cells. Fatty Acids protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
2 In addition, the results displayed that genistein promoted the phosphorylation of adenosine monophosphate-activated protein kinase (AMPK) suppressed by fatty acid, which were significantly weakened by compound C, an AMPK inhibitor. Fatty Acids protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
3 In addition, the results displayed that genistein promoted the phosphorylation of adenosine monophosphate-activated protein kinase (AMPK) suppressed by fatty acid, which were significantly weakened by compound C, an AMPK inhibitor. Fatty Acids protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
4 In addition, the results displayed that genistein promoted the phosphorylation of adenosine monophosphate-activated protein kinase (AMPK) suppressed by fatty acid, which were significantly weakened by compound C, an AMPK inhibitor. Fatty Acids protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
5 Taken all together, genistein is capable to ameliorate fat accumulation through regulation of fatty acid metabolism mediated by AMPK activation in BRL cells. Fatty Acids protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
6 PRACTICAL APPLICATION: Genistein is able to ameliorate fat accumulation through regulation of fatty acid metabolism mediated by AMPK activation in vitro. Fatty Acids protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens