Pub. Date : 1989 Feb 15
PMID : 2912553
3 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | Purification and characterization of cytochrome P-450 induced by benz(a)anthracene in mouse skin microsomes. | benz(a)anthracene | cytochrome P450, family 21, subfamily a, polypeptide 1 | Mus musculus | ||
| 2 | Topical application of benz(a)anthracene to mouse skin elicited a 2-fold increase in cytochrome P-450 content, with accompanying increases in monooxygenase activities such as benzo(a)pyrene hydroxylation, 7-ethoxycoumarin O-deethylation, and acetanilide 4-hydroxylation, in the microsomes. | benz(a)anthracene | cytochrome P450, family 21, subfamily a, polypeptide 1 | Mus musculus | ||
| 3 | The results indicate that, in mouse skin microsomes, a cytochrome P-450 induced by benz(a)anthracene is enzymatically and immunochemically similar to rat liver cytochrome P-450MC-1. | benz(a)anthracene | cytochrome P450, family 21, subfamily a, polypeptide 1 | Mus musculus | ||