Title : Induction of erythroid differentiation of K562 human leukemic cells by herbimycin A, an inhibitor of tyrosine kinase activity.

Pub. Date : 1989 Jan 15

PMID : 2910452






1 Functional Relationships(s)
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1 In order to understand the relationship between induction of differentiation and reduction of tyrosine phosphorylation by the c-abl gene product, the effect that herbimycin A, a selective inhibitor of intracellular tyrosine kinase activity, exerts on the differentiation of K562 cells was examined. herbimycin ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens