Title : Chemopreventive effects of atractylenolide II on mammary tumorigenesis via activating Nrf2-ARE pathway.

Pub. Date : 2017 Sep 29

PMID : 29100404






2 Functional Relationships(s)
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1 Our previous study indicated that atractylenolide II, which is an active component of Atractylodes macrocephala Koidz, is a potential activator of Nrf2-ARE signaling pathway. atractylenolide II NFE2 like bZIP transcription factor 2 Homo sapiens
2 Collectively, our results suggested that atractylenolide II could protect against mammary tumorigenesis both in vivo and in vitro via activating Nrf2-ARE signaling pathway, which supported atractylenolide II as a novel chemopreventive agent of breast cancer. atractylenolide II NFE2 like bZIP transcription factor 2 Homo sapiens