Title : A novel mammalian glucokinase exhibiting exclusive inorganic polyphosphate dependence in the cell nucleus.

Pub. Date : 2017 Dec

PMID : 29090276






2 Functional Relationships(s)
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1 BACKGROUND: Hexokinase and glucokinase enzymes are ubiquitously expressed and use ATP and ADP as substrates in mammalian systems and a variety of polyphosphate substrates and/or ATP in some eukaryotic and microbial systems. Adenosine Diphosphate glucokinase Homo sapiens
2 RESULTS: A novel mammalian glucokinase, highly responsive to hexametaphosphate (HMP) but not ATP or ADP as a phosphoryl donor is present in the nuclei of mammalian hepatocytes. Adenosine Diphosphate glucokinase Homo sapiens