Title : Overexpression of centromere protein K (CENP-K) gene in hepatocellular carcinoma promote cell proliferation by activating AKT/TP53 signal pathway.

Pub. Date : 2017 Sep 26

PMID : 29088763






1 Functional Relationships(s)
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1 Furthermore, we found that overexpression of CENP-K stimulated the tyrosine phosphorylation of the AKT and MDM2 proteins, but inhibited tyrosine phosphorylation of the TP53 protein. Tyrosine MDM2 proto-oncogene Homo sapiens