Pub. Date : 2017 Sep-Oct
PMID : 29072221
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Comparative evaluation of inhibitory effect of curcumin and doxycycline on matrix metalloproteinase-9 activity in chronic periodontitis. | Curcumin | matrix metallopeptidase 9 | Homo sapiens |
| 2 | Curcumin has anti-inflammatory effect and also downregulates MMP activity. | Curcumin | matrix metallopeptidase 9 | Homo sapiens |
| 3 | Thus, a study was conducted to evaluate the anti-inflammatory effect of curcumin by its inhibition of MMP-9 activity and compare the same with doxcycline, which has known anticollagenase activity. | Curcumin | matrix metallopeptidase 9 | Homo sapiens |
| 4 | Curcumin showed 61.01% reduction in the MMP-9 activity at 1500 mug/ml concentration and doxycycline showed 59.58% reduction in the MMP-9 activity at 300 mug/ml concentration. | Curcumin | matrix metallopeptidase 9 | Homo sapiens |
| 5 | CONCLUSION: The current study showed that curcumin has inhibitory effect on polymorphonuclear leukocyte-type MMP-9 involved in matrix degradation in periodontitis. | Curcumin | matrix metallopeptidase 9 | Homo sapiens |