Pub. Date : 2017 Nov-Dec
PMID : 29068698
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The Impact of Dietary Polyphenols on COX-2 Expression in Colorectal Cancer. | Polyphenols | prostaglandin-endoperoxide synthase 2 | Homo sapiens |
| 2 | Polyphenols influence the inflammatory process by controlling and inhibiting pro-inflammatory cytokines such as IL-1beta, IL-6, IL-8, and TNF-alpha, and cyclooxygenase-2 (COX-2) enzyme involved in the metabolism of arachidonic acid. | Polyphenols | prostaglandin-endoperoxide synthase 2 | Homo sapiens |
| 3 | Polyphenols influence the inflammatory process by controlling and inhibiting pro-inflammatory cytokines such as IL-1beta, IL-6, IL-8, and TNF-alpha, and cyclooxygenase-2 (COX-2) enzyme involved in the metabolism of arachidonic acid. | Polyphenols | prostaglandin-endoperoxide synthase 2 | Homo sapiens |
| 4 | This paper reviews the current state of knowledge concerning the potential of various dietary polyphenols to inhibit the effects of COX-2 in colon cancer, by examining the available evidence regarding the efficacy and safety of these compounds obtained from in vitro and animal studies. | Polyphenols | prostaglandin-endoperoxide synthase 2 | Homo sapiens |