Title : Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.

Pub. Date : 2018 Mar 6

PMID : 29065194






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1 Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-kappaB Signaling Pathway in Aged Rats. Nicotine brain-derived neurotrophic factor Rattus norvegicus
2 However, nicotine pre-treatment clearly reversed the surgical stress-induced decrease in both BDNF and p-TrkB expression in the hippocampus. Nicotine brain-derived neurotrophic factor Rattus norvegicus
3 Conclusions: Our results showed that nicotine-induced neuroprotection against POCD may involve activation of the BDNF/TrkB signaling pathway and inhibition of the NF-kappaB signaling pathway. Nicotine brain-derived neurotrophic factor Rattus norvegicus