Title : Further characterization of a somatic cell mutant defective in regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

Pub. Date : 1988 Nov

PMID : 2904178






1 Functional Relationships(s)
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1 In this report, we demonstrate that this mutant is defective in regulation of the mRNA levels for HMG-CoA reductase and HMG-CoA synthase by 25-hydroxycholesterol and mevinolin. 25-hydroxycholesterol 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens