PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2904178-4 1988 In this report, we demonstrate that this mutant is defective in regulation of the mRNA levels for HMG-CoA reductase and HMG-CoA synthase by 25-hydroxycholesterol and mevinolin. 25-hydroxycholesterol 140-161 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens 98-115