Title : Natural product celastrol suppressed macrophage M1 polarization against inflammation in diet-induced obese mice via regulating Nrf2/HO-1, MAP kinase and NF-κB pathways.

Pub. Date : 2017 Oct 16

PMID : 29040966






1 Functional Relationships(s)
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1 Celastrol down-regulated the mRNA levels of macrophage M1 biomarkers (e.g., IL-6, IL-1beta, TNF-alpha, iNOS) in cell culture and in mice. celastrol interleukin 1 beta Mus musculus