PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29040966-5 2017 Celastrol down-regulated the mRNA levels of macrophage M1 biomarkers (e.g., IL-6, IL-1beta, TNF-alpha, iNOS) in cell culture and in mice. celastrol 0-9 interleukin 1 beta Mus musculus 82-90