Title : Cu2+-Complex of hydrophilic nitrogen-rich polymer dots applied as a new MRI contrast agent.

Pub. Date : 2017 Oct 24

PMID : 29027548






5 Functional Relationships(s)
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1 The N-rich polymer dots are prepared from N-vinyl imidazole (VIm) by a one-pot hydrothermal synthesis at 220 C (24 h) and used later on to fabricate a Cu2+-PVIm dot complex via efficient incorporation of Cu2+ into aqueous medium. cupric ion vimentin Homo sapiens
2 The N-rich polymer dots are prepared from N-vinyl imidazole (VIm) by a one-pot hydrothermal synthesis at 220 C (24 h) and used later on to fabricate a Cu2+-PVIm dot complex via efficient incorporation of Cu2+ into aqueous medium. cupric ion vimentin Homo sapiens
3 The obtained Cu2+-PVIm dot complexes display relaxivity (r1 = 1.05 mM-1 s-1) two times higher than Cu2+ in aqueous solution (r1 = 0.43 mM-1 s-1) and three times higher than Cu2+ in aqueous solution coordinated with VIm monomers (r1 = 0.32 mM-1 s-1), which show a remarkable contrast enhancement for T1-weighted MRI while efficiently labeling MCF-7 cells and other biomedical applications. cupric ion vimentin Homo sapiens
4 The obtained Cu2+-PVIm dot complexes display relaxivity (r1 = 1.05 mM-1 s-1) two times higher than Cu2+ in aqueous solution (r1 = 0.43 mM-1 s-1) and three times higher than Cu2+ in aqueous solution coordinated with VIm monomers (r1 = 0.32 mM-1 s-1), which show a remarkable contrast enhancement for T1-weighted MRI while efficiently labeling MCF-7 cells and other biomedical applications. cupric ion vimentin Homo sapiens
5 The obtained Cu2+-PVIm dot complexes display relaxivity (r1 = 1.05 mM-1 s-1) two times higher than Cu2+ in aqueous solution (r1 = 0.43 mM-1 s-1) and three times higher than Cu2+ in aqueous solution coordinated with VIm monomers (r1 = 0.32 mM-1 s-1), which show a remarkable contrast enhancement for T1-weighted MRI while efficiently labeling MCF-7 cells and other biomedical applications. cupric ion vimentin Homo sapiens