Title : MYCN contributes to the malignant characteristics of erythroleukemia through EZH2-mediated epigenetic repression of p21.

Pub. Date : 2017 Oct 12

PMID : 29022893






1 Functional Relationships(s)
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1 In addition, Aurora inhibitor MLN8237 inhibited the proliferation of erythroleukemia cells through repression of MYCN/EZH2 axis, whereas it minimally affected the normal hematopoietic cells. MLN 8237 enhancer of zeste 2 polycomb repressive complex 2 subunit Homo sapiens