Title : Hormonal regulation of biliary calcium excretion in rats: inhibition of calcitonin action by alpha 1-adrenergic stimulation.

Pub. Date : 1988 Apr

PMID : 2899538






4 Functional Relationships(s)
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1 The effect of synthetic [Asu1,7] eel calcitonin (CT) and other hormones on biliary calcium excretion was investigated in rats cannulated bile duct. Calcium calcitonin-related polypeptide alpha Rattus norvegicus
2 Administration of CT (80 mU/100 g body weight) produced a significant increase in liver calcium and a corresponding elevation of bile calcium content. Calcium calcitonin-related polypeptide alpha Rattus norvegicus
3 Of these hormones and drugs, norepinephrine, a alpha-receptor mediator, clearly prevented CT effect on biliary calcium excretion. Calcium calcitonin-related polypeptide alpha Rattus norvegicus
4 The present study clearly demonstrates that biliary calcium excretion is stimulated by various hormones which increase calcium influx into liver cells, and suggests that the CT action may be inhibited by alpha 1-adrenergic stimulation. Calcium calcitonin-related polypeptide alpha Rattus norvegicus