Pub. Date : 2017 Oct 5
PMID : 28983097
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mutations of cortactin that prevent its tyrosine phosphorylation downregulate RhoA signaling and compromise the ability of epithelial cells to generate a contractile zonula adherens. | Tyrosine | ras homolog family member A | Homo sapiens |
| 2 | Here the authors report how tyrosine dephosphorylation of the cytoskeletal scaffold, cortactin, recruits the RhoA antagonist SRGAP1 to relax adherens junctions in response to HGF. | Tyrosine | ras homolog family member A | Homo sapiens |