Pub. Date : 2017 Oct
PMID : 28982598
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Methyleugenol protects against t-BHP-triggered oxidative injury by induction of Nrf2 dependent on AMPK/GSK3beta and ERK activation. | tert-Butylhydroperoxide | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 2 | Furthermore, Mlg exposure significantly lessened t-BHP-induced cytotoxicity and ROS production which were evidently abolished by treatment with AMPK and ERK inhibitors and Nrf2 siRNA. | tert-Butylhydroperoxide | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 3 | Accordingly, Mlg might exhibit a protective role against t-BHP-triggered cytotoxicity via the activation of the AMPK/GSK3beta- and ERK-Nrf2 signaling pathways. | tert-Butylhydroperoxide | NFE2 like bZIP transcription factor 2 | Homo sapiens |