Title : DKK4-knockdown enhances chemosensitivity of A549/DTX cells to docetaxel.

Pub. Date : 2017 Oct 1

PMID : 28981599






2 Functional Relationships(s)
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1 Moreover, DKK4-knockdown promoted the pro-apoptotic effect of docetaxel characterized with caspase 3 activation and inhibition of BCL-2 expression in A549/DTX cells, which was possibly mediated by inducing the activation of c-Jun N-terminal kinase (JNK)-related signaling pathway. Docetaxel mitogen-activated protein kinase 8 Homo sapiens
2 Moreover, DKK4-knockdown promoted the pro-apoptotic effect of docetaxel characterized with caspase 3 activation and inhibition of BCL-2 expression in A549/DTX cells, which was possibly mediated by inducing the activation of c-Jun N-terminal kinase (JNK)-related signaling pathway. Docetaxel mitogen-activated protein kinase 8 Homo sapiens