Title : Histamine inhibits interleukin 1 production by lipopolysaccharide-stimulated human peripheral blood monocytes.

Pub. Date : 1988 May

PMID : 2897711






1 Functional Relationships(s)
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1 The effect of histamine on IL-1 production was dose-dependent and significant at histamine concentrations of 10(-4)-10(-5) M. The histamine H2 receptor agonists dimaprit and 4-methylhistamine, but not the H1 receptor agonists 2-pyridylethylamine, aminoethylthiazole and 2-methylhistamine, modulated the IL-1 production in a similar manner to histamine. 2-(2-aminoethyl)pyridine interleukin 1 alpha Homo sapiens