Title : Icariin improves acute kidney injury and proteinuria in a rat model of pregnancy‑induced hypertension.

Pub. Date : 2017 Nov

PMID : 28944832






2 Functional Relationships(s)
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1 However, icariin treatment significantly reversed the L-NAME-induced downregulation of nephrin and upregulation of circulating and renal Ang II levels in PIH rats. icariin angiotensinogen Rattus norvegicus
2 These results demonstrated that icariin administration improved urinary protein excretion levels and renal tissue damage in PIH rats, and the underlying mechanism was mediated in part, via upregulation of nephrin expression and downregulation of Ang II. icariin angiotensinogen Rattus norvegicus