Pub. Date : 2017 Oct
PMID : 28928973
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Prospective replication study implicates the catechol-O-methyltransferase Val158Met polymorphism as a biomarker for the response to morphine in patients with cancer. | Morphine | catechol-O-methyltransferase | Homo sapiens |
| 2 | Previous studies indicate that a single nucleotide polymorphism in the catechol-O-methyltransferase (COMT) gene (rs4680; p.Val158Met) may present as a predictive biomarker for the response to morphine treatment. | Morphine | catechol-O-methyltransferase | Homo sapiens |
| 3 | Previous studies indicate that a single nucleotide polymorphism in the catechol-O-methyltransferase (COMT) gene (rs4680; p.Val158Met) may present as a predictive biomarker for the response to morphine treatment. | Morphine | catechol-O-methyltransferase | Homo sapiens |
| 4 | The required dose of morphine on day 1 was significantly higher for patients with the G/G genotype of COMT, compared with those with the A/A and A/G genotypes (P=0.013). | Morphine | catechol-O-methyltransferase | Homo sapiens |
| 5 | The results of the present study provide additional evidence that the COMT genotype may be a predictive biomarker for the response to morphine treatment. | Morphine | catechol-O-methyltransferase | Homo sapiens |