Title : PCDH8 inhibits glioma cell proliferation by negatively regulating the AKT/GSK3β/β-catenin signaling pathway.

Pub. Date : 2017 Sep

PMID : 28927088






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Restoration of PCDH8 decreased phosphorylated (p)-Rac-alpha serine/threonine-protein kinase (AKT) [Threonine (T)308/Serine (S)473] and p-glycogen synthase kinase-3beta (p-GSK3beta) (S9) protein expression, thereby reducing the level of beta-catenin when compared with the control. Serine protocadherin 8 Homo sapiens