| Protein Name | protocadherin 8 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 5100 |
| Gene Symbol | PCDH8 |
| UniProt | O95206 (PCDH8_HUMAN), A0A024QZ94 (A0A024QZ94_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
81
Total Number of Articles : 46 |
Description |
protocadherin 8 |
| Gene Summary |
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008] |
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| Properties | |