Pub. Date : 2017 Nov 20
PMID : 28919534
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Glutamate-induced rapid induction of Arc/Arg3.1 requires NMDA receptor-mediated phosphorylation of ERK and CREB. | Glutamic Acid | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | In addition, the phosphorylation of ERK and CREB, two downstream factors of NMDAR signaling, markedly increased after glutamate exposure. | Glutamic Acid | mitogen-activated protein kinase 1 | Homo sapiens |
| 3 | Blocking ERK and CREB activation via selective inhibitors partially prevented the glutamate-induced elevation of Arc/Arg3.1 protein levels. | Glutamic Acid | mitogen-activated protein kinase 1 | Homo sapiens |