Pub. Date : 2017 Nov
PMID : 28893623
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CYP17A1 inhibitor abiraterone, an anti-prostate cancer drug, also inhibits the 21-hydroxylase activity of CYP21A2. | abiraterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 2 | Abiraterone is an inhibitor of CYP17A1 which is used for the treatment of castration resistant prostate cancer. | abiraterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 3 | A loss of CYP21A2 activity in combination with reduction of CYP17A1 activities by abiraterone could result in lower cortisol levels and may require monitoring for any potential adverse effects. | abiraterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |