Pub. Date : 2017 Nov
PMID : 28882873
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | HDLc levels were significantly decreased by 29% (P=0.01) in Abca8b-/- mice on a high-cholesterol diet compared with wild-type mice, whereas hepatic overexpression of human ABCA8 in mice resulted in significant increases in plasma HDLc and the first steps of macrophage-to-feces reverse cholesterol transport. | Cholesterol | ATP binding cassette subfamily A member 8 | Homo sapiens |
| 2 | CONCLUSIONS: ABCA8 facilitates cholesterol efflux and modulates HDLc levels in humans and mice. | Cholesterol | ATP binding cassette subfamily A member 8 | Homo sapiens |