PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28882873-7 2017 HDLc levels were significantly decreased by 29% (P=0.01) in Abca8b-/- mice on a high-cholesterol diet compared with wild-type mice, whereas hepatic overexpression of human ABCA8 in mice resulted in significant increases in plasma HDLc and the first steps of macrophage-to-feces reverse cholesterol transport. Cholesterol 286-297 ATP binding cassette subfamily A member 8 Homo sapiens 172-177 28882873-10 2017 CONCLUSIONS: ABCA8 facilitates cholesterol efflux and modulates HDLc levels in humans and mice. Cholesterol 31-42 ATP binding cassette subfamily A member 8 Homo sapiens 13-18