Title : Cerebral ammonia metabolism in normal and hyperammonemic rats.

Pub. Date : 1987 Feb-Apr

PMID : 2888066






3 Functional Relationships(s)
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1 In contrast, the brain possesses only one major enzyme for the removal of exogenous ammonia, i.e., glutamine synthetase. Ammonia glutamate-ammonia ligase Rattus norvegicus
2 These data are consistent with the hypothesis that glutamine synthetase is the major enzyme for metabolism of endogenously--as well as exogenously--produced ammonia. Ammonia glutamate-ammonia ligase Rattus norvegicus
3 In the hyperammonemic rat brain, glutamine synthetase is still the only important enzyme for the removal of blood-borne ammonia. Ammonia glutamate-ammonia ligase Rattus norvegicus