Pub. Date : 2017
PMID : 28878681
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our previous studies suggested that alpha5-nAChR mediates nicotine-induced lung cancer cell proliferation, migration, and invasion in vitro. | Nicotine | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 2 | In vivo, alpha5-nAChR silencing inhibited the growth of lung tumors, especially in the context of nicotine exposure. | Nicotine | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 3 | These results reveal that alpha5-nAChR silencing inhibits the progression of nicotine-related NSCLC, making this receptor a potential pharmacological target for the treatment of nicotine-related lung carcinogenesis. | Nicotine | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 4 | These results reveal that alpha5-nAChR silencing inhibits the progression of nicotine-related NSCLC, making this receptor a potential pharmacological target for the treatment of nicotine-related lung carcinogenesis. | Nicotine | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |