Pub. Date : 2017
PMID : 28854431
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Iopromide caused elevation of SCr, BUN and NGAL level, decrease of endogenous creatinine clearance, morphological injury and tubular apoptosis, enhanced IL-1beta and IL-18 expression, and increased expression of S100A8/A9, TLR4 and NLRP3 inflammsome. | iopromide | NLR family, pyrin domain containing 3 | Rattus norvegicus |
| 2 | In NRK-52E cells, iopromide caused enhanced apoptotic rates and ROS generation, which could be ameliorated by inhibitor of TLR4 and NLRP3-siRNA. | iopromide | NLR family, pyrin domain containing 3 | Rattus norvegicus |