Title : Partial filling affinity capillary electrophoresis as a useful tool for fragment-based drug discovery: A proof of concept on thrombin.

Pub. Date : 2017 Sep 1

PMID : 28843566






1 Functional Relationships(s)
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1 To demonstrate the accuracy of our assay, the complex dissociation constants of three known thrombin inhibitors, namely benzamidine, p-aminobenzamidine and nafamostat were determined and found to be in good concordance with the previously reported values. nafamostat coagulation factor II, thrombin Homo sapiens