Pub. Date : 2017 Oct 15
PMID : 28842332
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | STATEMENT OF SIGNIFICANCE: In this study, we report the synthesis of the tumor acidity-activatable amorphous porous manganese phosphate nanoparticles and their application for a photoactivable synergistic nanosystem that imparts reactive oxygen species (ROS) induced cytotoxicity in synchrony with hypoxia-inducible factor 1alpha/vascular endothelial growth factor (HIF-1alpha/VEGF) inhibitor that suppresses tumor growth and treatment escape signalling pathway. | Reactive Oxygen Species | vascular endothelial growth factor A | Homo sapiens |
2 | STATEMENT OF SIGNIFICANCE: In this study, we report the synthesis of the tumor acidity-activatable amorphous porous manganese phosphate nanoparticles and their application for a photoactivable synergistic nanosystem that imparts reactive oxygen species (ROS) induced cytotoxicity in synchrony with hypoxia-inducible factor 1alpha/vascular endothelial growth factor (HIF-1alpha/VEGF) inhibitor that suppresses tumor growth and treatment escape signalling pathway. | Reactive Oxygen Species | vascular endothelial growth factor A | Homo sapiens |