PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28842332-7 2017 STATEMENT OF SIGNIFICANCE: In this study, we report the synthesis of the tumor acidity-activatable amorphous porous manganese phosphate nanoparticles and their application for a photoactivable synergistic nanosystem that imparts reactive oxygen species (ROS) induced cytotoxicity in synchrony with hypoxia-inducible factor 1alpha/vascular endothelial growth factor (HIF-1alpha/VEGF) inhibitor that suppresses tumor growth and treatment escape signalling pathway. Reactive Oxygen Species 229-252 vascular endothelial growth factor A Homo sapiens 377-381 28842332-7 2017 STATEMENT OF SIGNIFICANCE: In this study, we report the synthesis of the tumor acidity-activatable amorphous porous manganese phosphate nanoparticles and their application for a photoactivable synergistic nanosystem that imparts reactive oxygen species (ROS) induced cytotoxicity in synchrony with hypoxia-inducible factor 1alpha/vascular endothelial growth factor (HIF-1alpha/VEGF) inhibitor that suppresses tumor growth and treatment escape signalling pathway. Reactive Oxygen Species 254-257 vascular endothelial growth factor A Homo sapiens 377-381