Title : Impact of genotypic and phenotypic differences in sarcoma models on the outcome of photochemical internalization (PCI) of bleomycin.

Pub. Date : 2017 Dec

PMID : 28838761






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Glutathione depletion with the glutathione synthetase inhibitor buthionine sulfoximine increased the cytotoxic effect of the photochemical treatment (PDT) most strongly in the SK-LMS-1 cells, and reduced PCIBLM-induced H2AX activation in the MES-SA cells, but not in the SK-LMS-1 cells. Glutathione glutathione synthetase Homo sapiens