| Protein Name | glutathione synthetase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 2937 |
| Gene Symbol | GSS |
| UniProt | P48637 (GSHB_HUMAN), V9HWJ1 (V9HWJ1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
142
Total Number of Articles : 160 |
Description |
glutathione synthetase |
| Gene Summary |
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency. [provided by RefSeq, Jul 2008] |
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| Properties | |