Protein Name glutathione synthetase
Organism Homo sapiens
Gene ID 2937
Gene Symbol


UniProt P48637 (GSHB_HUMAN), V9HWJ1 (V9HWJ1_HUMAN)
Relationships Total Number of functionally related compound(s) : 142
Total Number of Articles : 160

glutathione synthetase

Gene Summary

Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency. [provided by RefSeq, Jul 2008]

  • glutathione synthetase
  • GSH synthetase
  • GSH-S
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