Title : Lipid droplets and lipotoxicity during autophagy.

Pub. Date : 2017

PMID : 28806138






3 Functional Relationships(s)
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1 In our recent study, we demonstrated that FAs released during MTORC1-regulated autophagy are selectively channeled by DGAT1 (diacylglycerol O-acyltransferase 1) into triacylglycerol (TAG)-rich LDs. Fatty Acids diacylglycerol O-acyltransferase 1 Homo sapiens
2 In our recent study, we demonstrated that FAs released during MTORC1-regulated autophagy are selectively channeled by DGAT1 (diacylglycerol O-acyltransferase 1) into triacylglycerol (TAG)-rich LDs. Fatty Acids diacylglycerol O-acyltransferase 1 Homo sapiens
3 These DGAT1-dependent LDs sequester FAs and prevent the accumulation of acylcarnitines, which otherwise directly disrupt mitochondrial integrity. Fatty Acids diacylglycerol O-acyltransferase 1 Homo sapiens