Pub. Date : 2017
PMID : 28804849
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ristocetin-induced platelet aggregation (RIPA) is used as an in vitro test to determine the presence and integrity of the platelet glycoprotein (GP) Ibalpha-V-IX complex and von Willebrand factor (VWF) interaction and is usually performed using platelet-rich plasma (PRP). | Ristocetin | von Willebrand factor | Homo sapiens |
| 2 | Ristocetin-induced platelet aggregation (RIPA) is used as an in vitro test to determine the presence and integrity of the platelet glycoprotein (GP) Ibalpha-V-IX complex and von Willebrand factor (VWF) interaction and is usually performed using platelet-rich plasma (PRP). | Ristocetin | von Willebrand factor | Homo sapiens |
| 3 | Impairment in the response of VWF/GPIbalpha-V-IX is measured with reference to several established concentrations of ristocetin and may indicate defects in VWF or in GPIbalpha-V-IX function. | Ristocetin | von Willebrand factor | Homo sapiens |
| 4 | For example, the correction of an abnormal RIPA trace after mixing PRP with normal plasma and rechallenging with ristocetin at 1.0 mg/mL suggests VWF function/quantity defect. | Ristocetin | von Willebrand factor | Homo sapiens |