Title : Ristocetin-Induced Platelet Aggregation (RIPA) and RIPA Mixing Studies.

Pub. Date : 2017

PMID : 28804849






4 Functional Relationships(s)
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1 Ristocetin-induced platelet aggregation (RIPA) is used as an in vitro test to determine the presence and integrity of the platelet glycoprotein (GP) Ibalpha-V-IX complex and von Willebrand factor (VWF) interaction and is usually performed using platelet-rich plasma (PRP). Ristocetin von Willebrand factor Homo sapiens
2 Ristocetin-induced platelet aggregation (RIPA) is used as an in vitro test to determine the presence and integrity of the platelet glycoprotein (GP) Ibalpha-V-IX complex and von Willebrand factor (VWF) interaction and is usually performed using platelet-rich plasma (PRP). Ristocetin von Willebrand factor Homo sapiens
3 Impairment in the response of VWF/GPIbalpha-V-IX is measured with reference to several established concentrations of ristocetin and may indicate defects in VWF or in GPIbalpha-V-IX function. Ristocetin von Willebrand factor Homo sapiens
4 For example, the correction of an abnormal RIPA trace after mixing PRP with normal plasma and rechallenging with ristocetin at 1.0 mg/mL suggests VWF function/quantity defect. Ristocetin von Willebrand factor Homo sapiens