Title : The Roles of NRF2 in Modulating Cellular Iron Homeostasis.

Pub. Date : 2018 Dec 10

PMID : 28793787






1 Functional Relationships(s)
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1 Constitutive NRF2 activation and subsequent deregulation of iron metabolism have been implicated in cancer development: NRF2-mediated upregulation of the iron storage protein ferritin or heme oxygenase 1 can lead to enhanced proliferation and therapy resistance. Iron heme oxygenase 1 Homo sapiens