Protein Name stearoyl-Coenzyme A desaturase 1
Organism Mus musculus
Gene ID 20249
Gene Symbol

Scd1

UniProt P13516 (ACOD1_MOUSE), Q547C4 (Q547C4_MOUSE)
Relationships Total Number of functionally related compound(s) : 288
Total Number of Articles : 373
Description

stearoyl-Coenzyme A desaturase 1

Gene Summary

Enables metal ion binding activity; palmitoyl-CoA 9-desaturase activity; and stearoyl-CoA 9-desaturase activity. Involved in several processes, including cholesterol esterification; positive regulation of cold-induced thermogenesis; and tarsal gland development. Acts upstream of or within several processes, including brown fat cell differentiation; monounsaturated fatty acid biosynthetic process; and white fat cell differentiation. Is integral component of endoplasmic reticulum membrane. Is expressed in several structures, including adipose tissue; central nervous system; cranium; integumental system; and liver. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 79. Orthologous to several human genes including SCD (stearoyl-CoA desaturase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • acyl-CoA desaturase 1
  • asebia
  • delta(9)-desaturase 1
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Properties