Title : Transforming Growth Factor β1/SMAD Signaling Pathway Activation Protects the Intestinal Epithelium from Clostridium difficile Toxin A-Induced Damage.

Pub. Date : 2017 Oct

PMID : 28784928






2 Functional Relationships(s)
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Protein Name
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1 TcdA increased the expression of TGF-beta1 and its receptor, TbetaRII, in vitro and in vivo TcdA induced nuclear translocation of the transcription factors SMAD2/3, a hallmark of TGF-beta1 pathway activation, both in IEC cells and in mouse ileal tissue. tcda SMAD family member 2 Mus musculus
2 TcdA increased the expression of TGF-beta1 and its receptor, TbetaRII, in vitro and in vivo TcdA induced nuclear translocation of the transcription factors SMAD2/3, a hallmark of TGF-beta1 pathway activation, both in IEC cells and in mouse ileal tissue. tcda SMAD family member 2 Mus musculus